Sometimes, it is also known as hematopoetin. They are produced by a sort of capillary in liver and kidney known as pertibular capillary. It has also few other biological functions other than creating red blood cells like, it plays vital role in creating a brain response to neuronal injury and involved in healing of wound process as well.
Exogenous erythropoietin which is made chemically to regulate and create red blood cells acts as a performance enhancing drug and they are well known as stimulating agent for erythropoiesis. Mainly, erythropoietin is produced by the fibro-blasts of pertibular in the rectal cortex. They are synthesized by renal peritubulars and they are produced in small quantity in liver. Erythropoietin has its chief outcome on red blood cells by endorsing red blood cell endurance during shielding these tissues from apoptosis. It also assists with a variety of expansion features concerned in the expansion of precursor red cells.
Erythropoietin is available as an agent for therapy and this is produced by combining the DNA technology to the mammalian cell culture. They are good to use in chronic diseases of kidney like anemia, the treatment of cancer and the critical illness. Epogen, Espogen, Epotin and Zyrop are few medicines which are used as therapy agents in various disease curing.
On the other side from benefits out of erythropoietin, it has some adverse effects as well. It can create cardiovascular complications if it is used to expand the level of hemoglobin more than 13 g/dl for the patients of kidney disease. |